Juvenile OLFM4-null mice are protected from sepsis
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چکیده
منابع مشابه
PPAR- –Null Mice Are Protected From High-Fat Diet–Induced Insulin Resistance
Peroxisome proliferator–activated receptor (PPAR)controls the expression of genes involved in lipid metabolism. PPARfurthermore participates to maintain blood glucose during acute metabolic stress, as shown in PPAR–null mice, which develop severe hypoglycemia when fasted. Here, we assessed a potential role for PPARin glucose homeostasis in response to long-term high-fat feeding. When subjected ...
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A physiological cross talk operates between the tumor suppressor protein p53 and the bradykinin B2 receptor (BdkrB2) during renal organogenesis. Thus, although BdkrB2 is a target for p53-mediated transcriptional activation, BdkrB2 is required to restrict p53 proapoptotic activity. We previously demonstrated that BdkrB2(-/-) embryos exposed to gestational salt stress develop renal dysgenesis as ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Renal Physiology
سال: 2020
ISSN: 1931-857X,1522-1466
DOI: 10.1152/ajprenal.00443.2019